PLoS Medicine: review time and acceptance speed

ISSN 1549-1277 · ISSN 1549-1676 · Public Library of Science · Medicine

Half of the articles PLoS Medicine accepted in 2025 were accepted within 197 days of submission (n = 149); the middle half took 167–249 days.

Submission → acceptance (2025)
197 days median
middle half 167–249 · n = 149
Acceptance → online
34 days median
middle half 26–48 · n = 149
Change since 2023
No clear change since 2023 (median 194 → 197 days; 90% CI -13 to +20 days).
Open access · fees
Open access (DOAJ) · $6,460

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does PLoS Medicine take to accept a paper?

days0751502253002020: middle half 142–249 days1862020n=3142021: middle half 144–259 days1962021n=2752022: middle half 137–225 days1812022n=1872023: middle half 152–235 days1942023n=1302024: middle half 126–229 days1662024n=1332025: middle half 167–249 days1972025n=149
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20251491671972490.0%0%
20241331261662290.0%0%
20231301521942350.0%0%
20221871371812250.0%0%
20212751441962593270.0%0%
20203141421862493100.0%0%

Distribution in 2025

0–29 days: 0% (0 articles)030–59 days: 1% (1 articles)3060–89 days: 2% (3 articles)6090–119 days: 6% (9 articles)90120–149 days: 10% (15 articles)120150–179 days: 15% (23 articles)150180–209 days: 21% (32 articles)180210–239 days: 15% (23 articles)210240–269 days: 9% (14 articles)240270–299 days: 7% (11 articles)270300–329 days: 5% (8 articles)300330–359 days: 1% (2 articles)330360+ days: 5% (8 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–2900.0%
30–5910.7%
60–8932.0%
90–11996.0%
120–1491510.1%
150–1792315.4%
180–2093221.5%
210–2392315.4%
240–269149.4%
270–299117.4%
300–32985.4%
330–35921.3%
360+85.4%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 34 days (middle half 26–48 days, n = 149).

From submission to online publication, the median was 236 days (middle half 196–286 days, n = 149).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Open access (listed in DOAJ). Listed APC: $6,460 (DOAJ).

Institutions reported paying a median of about $5,350 per article (2023–2025, 27 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJYes (DOAJ record)
Articles indexed for MEDLINE in 2025Yes
Retractions0 retracted articles among 996 added to PubMed in 2021–2025 (0.00 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.0% of 2025 articles
Publication volume173 articles added to PubMed in 2025 (+18% vs 2024).

Topics and scope

Medicine journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of PLoS Medicine, 197 days.

Paid APC medianDOAJMEDLINE
PLOS Global Public Health179 (2025, n = 997)$2,596$2,117 (103 payments)YesNo
Tropical Medicine & International Health129 (2025, n = 68)≈$3,400NoYes
The Lancet Global Health107 (2025, n = 270)$7,860$5,698 (53 payments)YesYes
BMJ Global Health200 (2025, n = 634)≈$4,827$4,286 (54 payments)YesYes
International Health130 (2025, n = 156)≈$2,973YesYes
Bulletin of the World Health Organization195 (2025, n = 101)No fee (DOAJ)YesYes
Journal of Public Health in Africa123 (2025, n = 109)≈$68YesNo
The Lancet Regional Health - Southeast Asia128 (2025, n = 130)$2,650YesNo

Frequently asked questions

How long does PLoS Medicine take to accept a paper?

Half of the articles PLoS Medicine accepted in 2025 were accepted within 197 days of submission (n = 149); the middle half took 167–249 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are PLoS Medicine articles published online?

Half of the articles accepted in 2025 appeared online within 34 days of acceptance (n = 149).

Does PLoS Medicine charge an article processing charge (APC)?

Listed APC: $6,460 (DOAJ).

Sources and method

Journal identity: ISSN-L 1549-1277; NLM ID 101231360; OpenAlex record. Speed figures use 149 articles accepted in 2025 with valid dates; excluded records for that year: none.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.