Nature Medicine: review time and acceptance speed

ISSN 1078-8956 · ISSN 1546-170X · Nature Portfolio · Medicine

Half of the articles Nature Medicine accepted in 2025 were accepted within 182 days of submission (n = 352); the middle half took 134–254 days.

Submission → acceptance (2025)
182 days median
middle half 134–254 · n = 352
Acceptance → online
44 days median
middle half 35–55 · n = 352
Change since 2023
No clear change since 2023 (median 174 → 182 days; 90% CI -8 to +23 days).
Open access · fees
Hybrid · ≈$12,690

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does Nature Medicine take to accept a paper?

days0751502253002020: middle half 77–246 days1712020n=2092021: middle half 75–241 days1432021n=2072022: middle half 98–267 days1692022n=2442023: middle half 124–240 days1742023n=2722024: middle half 118–229 days1702024n=3682025: middle half 134–254 days1822025n=352
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20253521341822543190.6%0%
20243681181702293140.3%0%
20232721241742403250.0%0%
2022244981692673340.0%0%
2021207751432413471.5%0%
2020209771712463341.4%0%

Distribution in 2025

0–29 days: 3% (12 articles)030–59 days: 4% (14 articles)3060–89 days: 5% (16 articles)6090–119 days: 8% (27 articles)90120–149 days: 13% (46 articles)120150–179 days: 16% (55 articles)150180–209 days: 14% (48 articles)180210–239 days: 9% (33 articles)210240–269 days: 7% (26 articles)240270–299 days: 8% (29 articles)270300–329 days: 4% (15 articles)300330–359 days: 3% (11 articles)330360+ days: 6% (20 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–29123.4%
30–59144.0%
60–89164.5%
90–119277.7%
120–1494613.1%
150–1795515.6%
180–2094813.6%
210–239339.4%
240–269267.4%
270–299298.2%
300–329154.3%
330–359113.1%
360+205.7%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 44 days (middle half 35–55 days, n = 352).

From submission to online publication, the median was 231 days (middle half 174–304 days, n = 352).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Hybrid (subscription journal with an open-access option). Listed APC: about $12,690 (as reported by OpenAlex).

Institutions reported paying a median of about $11,579 per article (2023–2025, 15 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJNo
Articles indexed for MEDLINE in 2025Yes
Retractions0 retracted articles among 1,948 added to PubMed in 2021–2025 (0.00 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.6% of 2025 articles
Publication volume516 articles added to PubMed in 2025 (+12% vs 2024).

Topics and scope

Medicine journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of Nature Medicine, 182 days.

Paid APC medianDOAJMEDLINE
Cell Reports Medicine232 (2025, n = 456)$5,790$5,240 (23 payments)YesYes
JCI Insight202 (2025, n = 489)$4,900$4,849 (54 payments)YesYes
Clinical & Translational Immunology147 (2025, n = 52)$3,380YesNo
Nature Biotechnology275 (2025, n = 141)≈$12,690$12,651 (5 payments)NoYes
Cancer Immunology Immunotherapy91 (2025, n = 333)$4,790YesYes
Seminars in Immunology82 (2025, n = 51)≈$4,370NoYes

Frequently asked questions

How long does Nature Medicine take to accept a paper?

Half of the articles Nature Medicine accepted in 2025 were accepted within 182 days of submission (n = 352); the middle half took 134–254 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are Nature Medicine articles published online?

Half of the articles accepted in 2025 appeared online within 44 days of acceptance (n = 352).

Does Nature Medicine charge an article processing charge (APC)?

Listed APC: about $12,690 (as reported by OpenAlex).

Sources and method

Journal identity: ISSN-L 1078-8956; NLM ID 9502015; OpenAlex record. Speed figures use 352 articles accepted in 2025 with valid dates; excluded records for that year: none.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.