PLoS Computational Biology: review time and acceptance speed

ISSN 1553-734X · ISSN 1553-7358 · Public Library of Science · Biochemistry, Genetics and Molecular Biology

Half of the articles PLoS Computational Biology accepted in 2025 were accepted within 201 days of submission (n = 798); the middle half took 148–267 days.

Submission → acceptance (2025)
201 days median
middle half 148–267 · n = 798
Acceptance → online
23 days median
middle half 15–35 · n = 798
Change since 2023
No clear change since 2023 (median 191 → 201 days; 90% CI -1 to +20 days).
Open access · fees
Open access (DOAJ) · $3,165

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does PLoS Computational Biology take to accept a paper?

days0751502253002020: middle half 128–233 days1762020n=7562021: middle half 137–245 days1822021n=8652022: middle half 142–249 days1902022n=8122023: middle half 146–251 days1912023n=6572024: middle half 152–268 days2002024n=7142025: middle half 148–267 days2012025n=798
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20257981482012673360.1%0%
20247141522002683440.0%0%
20236571461912513110.1%0%
20228121421902493160.1%0%
20218651371822453110.0%0%
20207561281762332940.0%0%

Distribution in 2025

0–29 days: 0% (1 articles)030–59 days: 1% (9 articles)3060–89 days: 3% (23 articles)6090–119 days: 8% (67 articles)90120–149 days: 13% (105 articles)120150–179 days: 15% (122 articles)150180–209 days: 13% (101 articles)180210–239 days: 14% (108 articles)210240–269 days: 9% (68 articles)240270–299 days: 8% (61 articles)270300–329 days: 6% (44 articles)300330–359 days: 4% (31 articles)330360+ days: 7% (58 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–2910.1%
30–5991.1%
60–89232.9%
90–119678.4%
120–14910513.2%
150–17912215.3%
180–20910112.7%
210–23910813.5%
240–269688.5%
270–299617.6%
300–329445.5%
330–359313.9%
360+587.3%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 23 days (middle half 15–35 days, n = 798).

From submission to online publication, the median was 227 days (middle half 172–298 days, n = 798).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Open access (listed in DOAJ). Listed APC: $3,165 (DOAJ).

Institutions reported paying a median of about $2,973 per article (2023–2025, 179 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJYes (DOAJ record)
Articles indexed for MEDLINE in 2025Yes
Retractions0 retracted articles among 4,127 added to PubMed in 2021–2025 (0.00 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.1% of 2025 articles
Publication volume865 articles added to PubMed in 2025 (+17% vs 2024).

Topics and scope

Biochemistry, Genetics and Molecular Biology journalsNeuroscience journalsMolecular Biology journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of PLoS Computational Biology, 201 days.

Paid APC medianDOAJMEDLINE
Molecular Systems Biology168 (2025, n = 99)$8,270$7,757 (14 payments)YesYes
Cell Systems312 (2025, n = 138)≈$9,350NoYes
Biosystems86 (2025, n = 187)≈$2,870NoYes
Bioinformatics168 (2025, n = 619)$3,798$3,855 (117 payments)YesYes
Briefings in Bioinformatics118 (2025, n = 738)$3,885$3,830 (20 payments)YesYes
Computational and Structural Biotechnology Journal91 (2025, n = 556)≈$3,404$3,325 (83 payments)YesNo
IET Systems Biology70 (2025, n = 56)$2,400YesYes
Frontiers in Computational Neuroscience77 (2025, n = 97)≈$3,850$3,203 (15 payments)YesNo
npj Systems Biology and Applications155 (2025, n = 152)$3,490$3,121 (12 payments)YesYes

Frequently asked questions

How long does PLoS Computational Biology take to accept a paper?

Half of the articles PLoS Computational Biology accepted in 2025 were accepted within 201 days of submission (n = 798); the middle half took 148–267 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are PLoS Computational Biology articles published online?

Half of the articles accepted in 2025 appeared online within 23 days of acceptance (n = 798).

Does PLoS Computational Biology charge an article processing charge (APC)?

Listed APC: $3,165 (DOAJ).

Sources and method

Journal identity: ISSN-L 1553-734X; NLM ID 101238922; OpenAlex record. Speed figures use 798 articles accepted in 2025 with valid dates; excluded records for that year: none.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.