PLoS Biology: review time and acceptance speed

ISSN 1544-9173 · ISSN 1545-7885 · Public Library of Science · Biochemistry, Genetics and Molecular Biology

Half of the articles PLoS Biology accepted in 2025 were accepted within 194 days of submission (n = 431); the middle half took 128–261 days.

Submission → acceptance (2025)
194 days median
middle half 128–261 · n = 431
Acceptance → online
28 days median
middle half 20–39 · n = 431
Change since 2023
No clear change since 2023 (median 197 → 194 days; 90% CI -16 to +10 days).
Open access · fees
Open access (DOAJ) · $5,500

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does PLoS Biology take to accept a paper?

days0751502253002020: middle half 145–251 days1962020n=3052021: middle half 120–258 days1942021n=2702022: middle half 122–240 days1802022n=2832023: middle half 141–258 days1972023n=3402024: middle half 141–271 days2012024n=3762025: middle half 128–261 days1942025n=431
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20254311281942613330.0%0%
20243761412012713430.3%0%
20233401411972583250.3%0%
20222831221802403160.0%0%
20212701201942583190.0%0%
20203051451962513320.0%0%

Distribution in 2025

0–29 days: 2% (8 articles)030–59 days: 5% (21 articles)3060–89 days: 7% (31 articles)6090–119 days: 9% (37 articles)90120–149 days: 9% (38 articles)120150–179 days: 11% (47 articles)150180–209 days: 13% (57 articles)180210–239 days: 13% (55 articles)210240–269 days: 10% (41 articles)240270–299 days: 7% (29 articles)270300–329 days: 5% (20 articles)300330–359 days: 3% (14 articles)330360+ days: 8% (33 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–2981.9%
30–59214.9%
60–89317.2%
90–119378.6%
120–149388.8%
150–1794710.9%
180–2095713.2%
210–2395512.8%
240–269419.5%
270–299296.7%
300–329204.6%
330–359143.2%
360+337.7%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 28 days (middle half 20–39 days, n = 431).

From submission to online publication, the median was 229 days (middle half 158–291 days, n = 431).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Open access (listed in DOAJ). Listed APC: $5,500 (DOAJ).

Institutions reported paying a median of about $5,948 per article (2023–2025, 98 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJYes (DOAJ record)
Articles indexed for MEDLINE in 2025Yes
Retractions2 retracted articles among 1,987 added to PubMed in 2021–2025 (1.01 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.0% of 2025 articles
Publication volume504 articles added to PubMed in 2025 (+17% vs 2024).

Topics and scope

Biochemistry, Genetics and Molecular Biology journalsNeuroscience journalsMolecular Biology journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of PLoS Biology, 194 days.

Paid APC medianDOAJMEDLINE
eLife235 (2025, n = 87)$3,750$2,405 (422 payments)YesYes
Current Biology147 (2025, n = 536)≈$7,030$6,607 (16 payments)NoYes
Communications Biology217 (2025, n = 1,969)$4,390$3,670 (197 payments)YesYes
BMC Biology186 (2025, n = 374)$3,790$2,968 (35 payments)YesYes
PLoS Genetics161 (2025, n = 373)$3,165$3,024 (77 payments)YesYes
BioEssays125 (2025, n = 103)≈$5,330NoYes
Cell287 (2025, n = 478)≈$11,400$10,148 (13 payments)NoYes
Current Opinion in Neurobiology127 (2025, n = 135)≈$4,320NoYes
Trends in Genetics59 (2025, n = 102)≈$7,030NoYes
Frontiers in Neural Circuits79 (2025, n = 57)≈$3,850$2,665 (6 payments)YesYes

Frequently asked questions

How long does PLoS Biology take to accept a paper?

Half of the articles PLoS Biology accepted in 2025 were accepted within 194 days of submission (n = 431); the middle half took 128–261 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are PLoS Biology articles published online?

Half of the articles accepted in 2025 appeared online within 28 days of acceptance (n = 431).

Does PLoS Biology charge an article processing charge (APC)?

Listed APC: $5,500 (DOAJ).

Sources and method

Journal identity: ISSN-L 1544-9173; NLM ID 101183755; OpenAlex record. Speed figures use 431 articles accepted in 2025 with valid dates; excluded records for that year: none.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.