Methods and Protocols: review time and acceptance speed

ISSN 2409-9279 · Multidisciplinary Digital Publishing Institute · Biochemistry, Genetics and Molecular Biology

Half of the articles Methods and Protocols accepted in 2025 were accepted within 51 days of submission (n = 157); the middle half took 42–65 days.

Submission → acceptance (2025)
51 days median
middle half 42–65 · n = 157
Acceptance → online
5 days median
middle half 3–8 · n = 157
Change since 2023
No clear change since 2023 (median 49 → 51 days; 90% CI -2 to +7 days).
Open access · fees
Open access (DOAJ) · ≈$2,200

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does Methods and Protocols take to accept a paper?

days0224568902020: middle half 24–48 days322020n=812021: middle half 27–52 days362021n=862022: middle half 32–58 days452022n=982023: middle half 37–61 days492023n=1202024: middle half 39–63 days492024n=1022025: middle half 42–65 days512025n=157
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20251574251650.6%99%
20241023949630.0%100%
20231203749610.0%100%
2022983245580.0%100%
2021862736522.3%100%
2020812432484.9%99%

Distribution in 2025

0–29 days: 6% (9 articles)030–59 days: 64% (101 articles)3060–89 days: 24% (37 articles)6090–119 days: 4% (7 articles)90120–149 days: 1% (2 articles)120150–179 days: 0% (0 articles)150180–209 days: 1% (1 articles)180210–239 days: 0% (0 articles)210240–269 days: 0% (0 articles)240270–299 days: 0% (0 articles)270300–329 days: 0% (0 articles)300330–359 days: 0% (0 articles)330360+ days: 0% (0 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–2995.7%
30–5910164.3%
60–893723.6%
90–11974.5%
120–14921.3%
150–17900.0%
180–20910.6%
210–23900.0%
240–26900.0%
270–29900.0%
300–32900.0%
330–35900.0%
360+00.0%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 5 days (middle half 3–8 days, n = 157).

From submission to online publication, the median was 58 days (middle half 47–71 days, n = 157).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Open access (listed in DOAJ). Listed APC: 1,800 CHF (about $2,200 at ECB rates of Sep 15, 2026; DOAJ).

Institutions reported paying a median of about $1,870 per article (2023–2025, 13 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJYes (DOAJ record)
Articles indexed for MEDLINE in 2025None found (the journal may be in PubMed through PubMed Central instead)
Retractions0 retracted articles among 558 added to PubMed in 2021–2025 (0.00 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.6% of 2025 articles
Publication volume152 articles added to PubMed in 2025 (+45% vs 2024).

Topics and scope

Biochemistry, Genetics and Molecular Biology journalsMolecular Biology journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of Methods and Protocols, 51 days.

Paid APC medianDOAJMEDLINE
Nature Protocols232 (2025, n = 171)NoYes
Biology Methods and Protocols79 (2025, n = 90)$1,067$1,241 (7 payments)YesNo
STAR Protocols94 (2025, n = 720)$1,920$1,022 (56 payments)YesYes
Nature Methods338 (2025, n = 209)≈$12,690$12,315 (5 payments)NoYes
Molecular Biotechnology128 (2025, n = 171)≈$3,790NoYes
Cell Reports Methods210 (2025, n = 178)$4,970$5,028 (17 payments)YesYes
Methods81 (2025, n = 157)≈$3,600NoYes
Biological Procedures Online93 (2025, n = 62)$3,590YesNo
Nucleic Acids Research152 (2025, n = 1,496)$4,192$3,862 (247 payments)YesYes
Nature Biomedical Engineering482 (2025, n = 202)≈$12,690NoYes

Frequently asked questions

How long does Methods and Protocols take to accept a paper?

Half of the articles Methods and Protocols accepted in 2025 were accepted within 51 days of submission (n = 157); the middle half took 42–65 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are Methods and Protocols articles published online?

Half of the articles accepted in 2025 appeared online within 5 days of acceptance (n = 157).

Does Methods and Protocols charge an article processing charge (APC)?

Listed APC: 1,800 CHF (about $2,200 at ECB rates of Sep 15, 2026; DOAJ).

Sources and method

Journal identity: ISSN-L 2409-9279; NLM ID 101720073; OpenAlex record. Speed figures use 157 articles accepted in 2025 with valid dates; excluded records for that year: none.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.