iScience: review time and acceptance speed

ISSN 2589-0042 · Cell Press · Biochemistry, Genetics and Molecular Biology

Half of the articles iScience accepted in 2025 were accepted within 182 days of submission (n = 2,505); the middle half took 133–254 days.

Submission → acceptance (2025)
182 days median
middle half 133–254 · n = 2,505
Acceptance → online
4 days median
middle half 3–5 · n = 2,506
Change since 2023
Slower than 2023: the median rose from 158 to 182 days (90% CI +19 to +29 days).
Open access · fees
Open access (DOAJ) · $3,240

Accepted articles only · dates deposited by the publisher in PubMed · data as of Sep 15, 2026

Plan submissions to a deadline — free

How long does iScience take to accept a paper?

days0751502253002020: middle half 82–176 days1192020n=1,0682021: middle half 95–194 days1392021n=1,3892022: middle half 110–213 days1532022n=1,9122023: middle half 114–216 days1582023n=2,5802024: middle half 124–223 days1672024n=2,6612025: middle half 133–254 days1822025n=2,505
Line = median; shaded box = middle half of articles (25th–75th percentile). Year of acceptance.
Days from submission to acceptance, by year of acceptance
YearArticles (n)25th pctMedian75th pct90th pctAccepted <14 daysHave a revised date
20252,5051331822543490.0%100%
20242,6611241672233030.0%100%
20232,5801141582162900.0%100%
20221,9121101532132920.1%100%
20211,389951391942660.0%100%
20201,068821191762510.1%100%

Distribution in 2025

0–29 days: 0% (3 articles)030–59 days: 1% (22 articles)3060–89 days: 5% (135 articles)6090–119 days: 11% (279 articles)90120–149 days: 17% (424 articles)120150–179 days: 14% (362 articles)150180–209 days: 13% (319 articles)180210–239 days: 10% (240 articles)210240–269 days: 8% (195 articles)240270–299 days: 5% (129 articles)270300–329 days: 4% (102 articles)300330–359 days: 2% (60 articles)330360+ days: 9% (235 articles)360+days from submission to acceptance (30-day bins)
Show as a table
DaysArticlesShare
0–2930.1%
30–59220.9%
60–891355.4%
90–11927911.1%
120–14942416.9%
150–17936214.5%
180–20931912.7%
210–2392409.6%
240–2691957.8%
270–2991295.1%
300–3291024.1%
330–359602.4%
360+2359.4%

From acceptance to online publication

After acceptance, half of the 2025 articles appeared online within 4 days (middle half 3–5 days, n = 2,506).

From submission to online publication, the median was 188 days (middle half 140–260 days, n = 2,505).

Read these numbers carefully

  • These times describe articles the journal accepted. Rejected manuscripts never appear in public data, so they cannot tell you how long a rejection takes.
  • Dates are the ones the publisher deposited with PubMed. Some publishers record the date a revised manuscript arrived as the submission date, which makes review look faster.
  • Invited articles and special issues can move faster than regular submissions.

Open access status and publishing fees

Open access (listed in DOAJ). Listed APC: $3,240 (DOAJ).

Institutions reported paying a median of about $3,046 per article (2023–2025, 266 reported payments in OpenAPC; converted from euros at yearly ECB average rates).

Many journals waive or reduce fees for authors from eligible countries or institutions with publishing agreements — check with the journal and your library.

Integrity and indexing signals

Facts from public records, shown without judgement. See the methodology for why each can be worth a closer look.

Listed in DOAJYes (DOAJ record)
Articles indexed for MEDLINE in 2025None found (the journal may be in PubMed through PubMed Central instead)
Retractions3 retracted articles among 11,646 added to PubMed in 2021–2025 (0.26 per 1,000), per the Retraction Watch Database.
Accepted within 14 days of submission0.0% of 2025 articles
Publication volume2,582 articles added to PubMed in 2025 (-8% vs 2024).

Topics and scope

Biochemistry, Genetics and Molecular Biology journalsMolecular Biology journals

Similar journals — faster or cheaper, side by side

Journals publishing on the most similar topics (OpenAlex), ordered by similarity. Only 2025 figures are compared with the 2025 median of iScience, 182 days.

Paid APC medianDOAJMEDLINE
Cell Reports204 (2025, n = 1,534)$5,790$5,172 (140 payments)YesYes
Communications Biology217 (2025, n = 1,969)$4,390$3,670 (197 payments)YesYes
Cell Discovery177 (2025, n = 67)$3,690YesNo
MedComm256 (2025, n = 464)$3,850YesNo
Signal Transduction and Targeted Therapy177 (2025, n = 402)$4,170$3,146 (10 payments)YesYes
Molecular Biomedicine212 (2025, n = 140)$2,990YesYes
Journal of Molecular Cell Biology163 (2025, n = 62)$2,730YesYes
Protein & Cell76 (2025, n = 68)$2,570YesYes
Life Science Alliance166 (2025, n = 155)$3,500$3,867 (92 payments)YesYes
Cell Research162 (2025, n = 59)≈$5,190NoYes

Frequently asked questions

How long does iScience take to accept a paper?

Half of the articles iScience accepted in 2025 were accepted within 182 days of submission (n = 2,505); the middle half took 133–254 days. Based on dates in PubMed for accepted articles only.

How long after acceptance are iScience articles published online?

Half of the articles accepted in 2025 appeared online within 4 days of acceptance (n = 2,506).

Does iScience charge an article processing charge (APC)?

Listed APC: $3,240 (DOAJ).

Sources and method

Journal identity: ISSN-L 2589-0042; NLM ID 101724038; OpenAlex record. Speed figures use 2,505 articles accepted in 2025 with valid dates; excluded records for that year: over 4 years 1.

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Data sources. Submission, acceptance and publication dates: Courtesy of the U.S. National Library of Medicine (PubMed, entries through Sep 15, 2026). NLM does not endorse Journal Clock, and these figures may not reflect the most current PubMed data. Journal fees and open-access listing: DOAJ (CC0, retrieved Sep 16, 2026). Fees paid by institutions: OpenAPC (Open Database License, retrieved Sep 16, 2026). Retractions: Retraction Watch Database via Crossref (retrieved Sep 16, 2026). Journal identifiers and topics: OpenAlex (CC0). Currency conversion: ECB reference rates (Sep 15, 2026). How these numbers are calculated · For organisations.